Determination of Ibuprofen and Paracetamol in Binary Mixture Using Chemometric-Assisted Spectrophotometric Methods

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Determination of Ibuprofen and Paracetamol in Binary Mixture Using Chemometric-Assisted Spectrophotometric Methods

Three methods are presented for simultaneous determination of ibuprofen and paracetamol without previous separation. The first method depends on first derivative UV spectrophotometry, with zero-crossing measurement. The first derivative amplitudes at 230 and 290 nm were selected for the assay of ibuprofen and paracetamol, respectively. The second method depends on first derivative of the ratio-...

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Simultaneous spectrophotometric determination of paracetamol, phenylephrine and chlropheniramine in pharmaceuticals using chemometric approaches

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UV Spectrophotometric Simultaneous Determination of Paracetamol and Ibuprofen in Combined Tablets by Derivative and Wavelet Transforms

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ژورنال

عنوان ژورنال: American Journal of Applied Sciences

سال: 2008

ISSN: 1546-9239

DOI: 10.3844/ajassp.2008.1005.1012